The Hashirama Cell

While Victor looks on, the Leaf team of Boruto, Konohamaru, Mitsuki, Sarada, and Mugino struggles to subdue a berserk Anato. Boruto hesitates to strike him hard because of a vow he made to Anato's wife Mia, which Mugino reads as weakness, so Konohamaru proposes a binding technique instead. Anato tears loose of the restraint and lashes out, and when Mitsuki pins him with a mass of snakes, one of the serpents rips away part of Anato's arm as he breaks the hold once more.

Victor's guards drive Anato back with their Scientific Ninja Tools, then their employer scolds them for the botched capture and sends the shinobi home, promising his company will look after the sick man. Boruto quietly pockets Anato's wedding ring, stung by how the mission fell apart. Not long after, Mitsuki notices his bitten arm has gone numb, and an odd substance begins creeping outward from the wound.

Mugino leads the group to a nearby physician, Yubina, who heals Boruto's hand with a rough grip and then studies Mitsuki, concluding an outside material has entered his body. Because Sarada has trained a little in Medical Ninjutsu, Yubina keeps her inside to assist while the rest wait beyond the door.

Yubina draws a splinter of wood out of Mitsuki and remarks that his unusual physiology is likely why he survived. She reveals the fragment was formed through Wood Release, which points back to the cells of Hashirama Senju. Mugino doubts a man like Anato could carry such genetic material, but Yubina produces a second patient, Kona, showing the same signs. She hopes Mitsuki's resistance can help her cure the stricken man, who was simply abandoned unconscious at her clinic.

Separately, Victor returns to a laboratory where Anato once worked, learns an item is still unaccounted for, and coldly orders Anato killed. A report also reaches him about a gap between the number of people sent out to search and the bodies later recovered.

The chapter belongs to the Kara Actuation Arc and first screened in Japan on 2 August 2020, with the English broadcast following on 17 May 2022. Its opening theme is Starting and Growing and the closing theme is Maybe I. Yubina links the Hashirama-cell rumor to an illicit trade she has heard about, and both Mugino and Konohamaru grow uneasy because the only black market in the region operates out of the Land of Silence.