The Four Supreme Generals are the elite Beastman commanders of Lordgenome's Human Eradication Army: Thymilph, Adiane, Cytomander, and Guame. Each operates from a mobile Dai-Gun fortress, and their names encode a double homage to East Asian mythology and the chemistry of DNA.
Answering directly to the Spiral King Lordgenome, the Four Supreme Generals occupy the top of the Human Eradication Army's command structure. All four are Beastmen, and each makes a Dai-Gun, one of the walking fortresses that anchor their forces, his or her headquarters. The group is listed as defunct.
The generals lead the military charged with hunting down humans on the surface, directing the wider Beastman campaign in Lordgenome's name. Within the Human Eradication Army, each of the four commands forces of his or her own while remaining subordinate only to the Spiral King himself.
The group consists of Thymilph, Adiane, Cytomander, and Guame. Their designs draw on the four legendary guardian beasts of Chinese and Japanese tradition: Guame corresponds to Genbu the Black Turtle, Thymilph to Byakko the White Tiger, Adiane to Seiryu the Blue Dragon, and Cytomander to Suzaku the Vermillion Bird. Their names layer in a second reference, deriving from the four nucleobases that make up DNA: guanine, thymine, adenine, and cytosine.

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The Four Supreme Generals are Thymilph, Adiane, Cytomander, and Guame, the elite Beastman commanders who answer directly to the Spiral King Lordgenome within the Human Eradication Army.
Each of the Four Supreme Generals commands a division of Lordgenome's Human Eradication Army from a mobile Dai-Gun fortress, hunting down humans who reach the surface.
The Four Supreme Generals' designs draw on the four guardian beasts of Chinese and Japanese tradition: Guame corresponds to Genbu the Black Turtle, Thymilph to Byakko the White Tiger, Adiane to Seiryu the Blue Dragon, and Cytomander to Suzaku the Vermillion Bird.
The names Thymilph, Adiane, Cytomander, and Guame derive from the four nucleobases that make up DNA: thymine, adenine, cytosine, and guanine.
No. The Four Supreme Generals are listed as defunct, as the group ended with Lordgenome's defeat and the fall of the Human Eradication Army.
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