During Stardust Crusaders, Nukesaku is a lowly vampire servant haunting DIO's mansion. With no Stand to call his own, he is belittled by DIO's stronger agents and reduced to a reluctant guide and a target for beatings. He counts as one of the final vampires the series ever depicts.
Nukesaku is a small, chalk-pale male vampire with a mane of long, matted hair, and the rear of his skull holds a second, feminine face above breasts on his back that a breastplate keeps hidden whenever he takes his true shape. For dress he layers a dark jumpsuit under a mismatched vest, adding boots, a loincloth, rings looped over his wrists and ankles, plus an animal-print cap. When disguised as a woman he swaps this for plain earrings, a modest dress, and a fashionable belt, and the rear face with its hair faintly recalls Yukako Yamagishi.
Nukesaku nurses a deep inferiority complex, since DIO's other minions sneer at his powers and shut him out of every fight. Once they fall, he seizes the moment to show his worth against Jotaro Kujo and the crusaders, only to fumble it through careless handling of his own dislocated parts. Even while herding the group up toward DIO's tower, he clings to the sinister hope that his master will use the chance to crush the Joestars, and he is stunned when DIO instead betrays, humiliates, and kills him, proving that even DIO deemed his gifts worthless.
Long dismissed as dead weight by DIO's circle for having no Stand, Nukesaku is saddled with the mocking title "The Idiot," and the guards who remain warn they will kill him should he butt into their fights. It is only once the last defenders fall, among them Telence T. D'Arby, Kenny G., and Vanilla Ice, that he glimpses an opening.
He plays the part of a helpless woman said to be trapped inside the mansion, hoping to lure the crusaders close, but Star Platinum answers with a fist to his face. Jotaro spells out his error: when he clasped his hands, he neglected that his thumbs faced the wrong way. Marched ahead to guide the group toward DIO's coffin, he assumes his master will ambush them, yet on raising the lid he discovers himself sliced apart within it, thrown away by DIO as useless.
Being a vampire, Nukesaku can unhinge and shuffle his body parts, a knack he combines with the extra face to sell the woman disguise, though he curiously lacks the raw superhuman might that most of his kind wield.

Naruto vs Luffy with the twist nobody asked for: Luffy tickled Hinata on date night, and she kind of liked it. We break down the whole fight and commit to a winner....

There are no women on Namek. That isn't an oversight, it's the biology. Why we handed Piccolo the one thing his own species rules out, and why it had to be trap soul....
Nukesaku is a name that reflects the character's mocking nicknames in the story, Loser and The Idiot, used because DIO's other minions consider him weak for having no Stand. The name is also connected to the song Loser by Beck.
Nukesaku is killed by his own master, DIO, in Stardust Crusaders. After leading Jotaro Kujo and the other crusaders toward DIO's coffin in hopes of an ambush, he opens the lid and discovers he has been sliced apart and discarded as useless.
No, Nukesaku is not DIO. He is a lowly vampire servant, referred to as DIO's manservant, who is looked down on by DIO's stronger agents for having no Stand of his own.
Nukesaku is a small, chalk-pale vampire with long, matted hair. The back of his skull holds a second, feminine face above breasts on his back, which he normally keeps hidden beneath a breastplate.
As a vampire, Nukesaku can unhinge and shuffle his own body parts, a trait he combines with his extra face to disguise himself as a woman. Unusually for his kind, he lacks the raw superhuman strength that most vampires possess.
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