Locacaca 6251

Locacaca 6251 is an experimental medicine developed from the Locacaca fruit by the higher-ups of the Locacaca Organization, who operated out of TG University Hospital. Its name blends the plant it derives from with the JoJo6251 art book. Satoru Akefu presents it publicly as a breakthrough in regenerative medicine, pitching it as a route to exchange one's way toward safe, restored health.

The drug comes as a liquid swallowed by mouth, and a 150 gram dose triggers regeneration shortly after ingestion. What it offers is a laboratory-tuned version of the raw fruit's equivalent exchange, and it works with far greater force. A single dose mended a whole cluster of Josuke Higashikata's wounds, several of them potentially fatal, yet the price it extracted was mild. Apart from his left eye, Josuke lost only small patches of skin across his face and neck, showing that the formula was engineered to maximize healing while suppressing the deadly side effects of the natural fruit. Even so, Akefu concedes that the drug is unfinished, a point underlined by the vision Josuke permanently lost in that eye.

Josuke Higashikata is the character shown using the drug, taking a vial to heal his injuries before he ultimately destroys the substance himself. Satoru Akefu stands as its developer and public spokesman, having unveiled it during his presentation on regenerative treatment.