Self-Detonation builds an explosion inside the wielder's own flesh and lets it go, usually destroying them in the process. The Villain Factory's engineered Bombers exist to deliver it, and the Quirk anchors one of Vigilantes' ugliest ideas: people manufactured as disposable ordnance.
Also called simply Detonation, this Emitter Quirk shows up in Chapter 46 of My Hero Academia: Vigilantes and reaches the adaptation in that series' Episode 22. Its range is close, for the obvious reason that the bomb and the bomber are the same object.
It is far from unique in the wider franchise. The Self-Destruct power All For One quietly slipped to Lady Nagant and the Burst Quirk carried by a winged Near High-End Nomu both work along the same lines, triggered remotely by someone else and wrecking the person they belong to. All three lead back to the same man: he armed Lady Nagant personally, the Nomu are his creations, and the Villain Factory operates within his orbit. That common thread raises the possibility that these powers are one Quirk, copied and handed out under different names.
Explosive force gathers inside the body itself. The affected area puffs up and starts to glow as energy pools there, then goes off. Yield depends on who is carrying it: among the Bombers, bulkier specimens produce bigger blasts, though even the runts hit hard enough to do real harm.
Control is the ugly part. The Bombers have no meaningful will of their own and never trigger the blast on their own initiative, waiting instead for a command, and the Quirk appears to be switchable by an outside operator holding the right device. The result is normally death or dismemberment for the user, unless their body has been altered to grow back what it loses. The Anonymous carry a diluted version whose blasts fall well short of the Bombers' output, a gap they close by swarming in large numbers.
The Bombers are living munitions, and the Villain Factory's operatives spend them accordingly, ordering suicide runs that leave heavy destruction behind. The Factory also engineers around the Quirk's fatal drawback by stacking it with other powers so the Next-Level Villain survives the trigger. The Multi-Armed Bomber is the showcase: fitted with a regeneration Quirk, it throws detonating punches, regrows the arm it just lost, and throws another, and it can pack extra force into a fist for a heavier hit.
Number 6 runs the same principle on a human frame. His strikes cost him his arms every time, but Bombify cells combined with his regenerative ability and Overclock put the limbs back instantly, letting him keep swinging. The Anonymous round out the roster with their weaker mass-produced variant.

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Self-Detonation is carried by the Villain Factory's engineered Bombers, as well as the villain Number 6 and the mass-produced Anonymous, all introduced in My Hero Academia: Vigilantes.
Self-Detonation is an Emitter Quirk that builds an explosion inside the user's own body and releases it, usually destroying the user in the process.
Because the Bombers have no meaningful will of their own, using Self-Detonation typically kills or dismembers them unless their bodies have been altered to regrow what they lose.
Self-Detonation resembles the Self-Destruct power All For One gave Lady Nagant and the Burst Quirk carried by a winged Near High-End Nomu, both of which are triggered remotely and destroy the user's own body.
The Multi-Armed Bomber is engineered with a regeneration Quirk, letting it throw a detonating punch, regrow the lost arm, and throw another, keeping the attack going despite the Quirk's normally fatal cost.
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