Chapter 349 fills in Jūgo's backstory as Sasuke's new team nears the prison holding him. Karin explains how Jūgo's blood gave rise to Orochimaru's cursed seals, just as one unhinged captive breaks loose.
Karin cautions Sasuke about Jūgo, though he shows no worry at all. Suigetsu, who knows next to nothing about the man, asks what makes him such a concern.
Karin recounts that Jūgo handed himself over to Orochimaru as a prisoner, hoping to be cured of the violent urges he cannot control. The experiments Orochimaru ran on him became the basis for the Juinjutsu, the cursed seals. Now that Orochimaru is dead, the many seal-bearers held at Jūgo's prison have descended into chaos.

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"At the Northern Hideout" is chapter 349 of the Naruto manga, and it reveals Jugo's backstory as Sasuke's new team closes in on the prison holding him, while Karin explains how Jugo's blood led to Orochimaru's cursed seals.
Karin warns Sasuke about Jugo because of the danger he poses, though Sasuke shows no concern, and Suigetsu, who knows little about Jugo, asks what makes him so risky.
According to Karin, Jugo willingly turned himself over to Orochimaru as a prisoner hoping to be cured of uncontrollable violent urges, and the experiments performed on him became the basis for Orochimaru's cursed seal technique, the Juinjutsu.
As Sasuke's group nears the facility, one of the seal-bearing prisoners, whose fellow captives have descended into chaos since Orochimaru's death, breaks free and attacks the group, but Sasuke defeats him with little effort.
"At the Northern Hideout" appears in volume 38 during the Itachi Pursuit Mission arc and was first published in Japan on April 23, 2007.
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