KYP is a chemical gas employed by the Yeti Cool Brothers on Punk Hazard. Breathing it in leaves a target dazed and stumbling as though heavily drunk, which the giants exploit to drop their foes without a fight.
KYP is an inhalant weapon that mimics the effects of alcohol intoxication. The Yeti Cool Brothers load it into bullets, turning the gas into a reliable tool for disabling enemies from a distance rather than relying on brute force. Its debut came when the brothers turned it against members of the Straw Hat crew.
When the gas reaches a victim's lungs, it scrambles their senses much like being drunk, sapping coordination and awareness until they collapse. Because the impairment runs on the same principle as alcohol, anyone with a strong tolerance for drink can shrug off part of the effect. Zoro and Nami both showed unusual resistance, staying functional where others would have been overwhelmed, since their bodies were used to handling liquor.
The Yeti Cool Brothers are the sole wielders of KYP. They used the gas-filled rounds to knock out Zoro, Brook, and Sanji, the last of whom was occupying Nami's body at the time. Thanks to that high alcohol tolerance, the swordsman and the navigator's borrowed form held out longer than the rest before the gas took its toll.

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KYP is a chemical gas weapon used by the Yeti Cool Brothers on Punk Hazard, mimicking the effects of alcohol intoxication in anyone who breathes it in. They load it into bullets to disable enemies from a distance without needing brute force.
Once inhaled, KYP scrambles a victim's senses much like drunkenness, sapping their coordination and awareness until they collapse. Because it works on the same principle as alcohol, people with a strong tolerance for drink can resist part of its effect.
The Yeti Cool Brothers are the only known users of KYP, firing gas-filled bullets to knock out members of the Straw Hat crew on Punk Hazard.
Zoro and Nami's body, which Sanji was occupying at the time, resisted the KYP gas longer than the others, thanks to their unusually high alcohol tolerance.
KYP first appears in Chapter 669 and Episode 595 of One Piece, when the Yeti Cool Brothers use it against the Straw Hats on Punk Hazard.
Looking for more on KYP? The One Piece Wiki on Fandom has a dedicated page with community notes.
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