
Titled "CANDY," this chapter reveals the sinister truth behind the giant children. Chopper diagnoses a hidden addiction to the restricted stimulant NHC10, the crew restrains the rampaging kids, and Caesar dispatches the silhouetted Yeti Cool Brothers to hunt the scattered Straw Hats.
While Franky fumbles to operate Chopper's shifting forms, the crew sorts out who should chase the wandering samurai. Sanji and Brook get the assignment, with Nami shoving Zoro along too so the cook's rivalry will keep his perversions in check. The remaining members debate priorities, agreeing that restoring their original bodies and minding the rescued children come first. Chopper finishes examining the kids just as the largest of them, Sind, buckles over in agony, the rest soon clutching their heads in the same sudden pain.
Questioning Sind, Chopper learns the children receive daily candy that makes them feel wonderful and eases their hurt. His tests expose the real cause: trace doses of NHC10, a powerful stimulant outlawed worldwide for its addictiveness, fed to them steadily so they cannot leave the facility. Brownbeard refuses to hear a word against his savior. When Sind is denied the candy, his eyes redden and he flies into a violent rage, hurling Luffy aside. The other youngsters reveal they arrived at normal size and only ballooned the longer they stayed, growth Chopper attributes to forced pituitary experiments rather than any illness.

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Usopp puts the withdrawing children to sleep with a new Burst Sleep Star, and the larger ones are chained to stop another rampage. Chopper and Nami stay behind as Luffy's group sets off to confront the lab's master. Elsewhere, Zoro, Sanji, and Brook lie collapsed in the snow amid two trails of enormous barefoot prints. Inside the facility, Caesar cradles Smoker's stolen heart and confirms he has loosed two hired killers, the Yeti Cool Brothers, after the crew. The cover story shows Magellan, now Impel Down's vice warden and the object of Sadi's affection.
In Chapter 665, titled CANDY, Chopper diagnoses the giant children's addiction to the outlawed stimulant NHC10, the crew restrains the kids as they go into withdrawal, and Caesar Clown sends the Yeti Cool Brothers after the scattered Straw Hats.
Chopper determines the giant children were not sick at all but ballooned in size due to forced pituitary experiments, while daily doses of the outlawed stimulant NHC10 kept them dependent and unable to leave the facility.
When the largest child, Sind, is denied his usual candy, his eyes turn red and he flies into a violent withdrawal rage, hurling Luffy aside before Usopp puts him and the other children to sleep with his new Burst Sleep Star.
Caesar Clown, while cradling Smoker's stolen heart, confirms he has sent two hired killers called the Yeti Cool Brothers after the crew, having already left Zoro, Sanji, and Brook unconscious in the snow.
Sanji and Brook are assigned to pursue the wandering samurai, with Nami sending Zoro along as well so his rivalry with Sanji will keep the cook's habits in check.
Looking for more on Chapter 665? The One Piece Wiki on Fandom has a dedicated page with community notes.
View on FandomThis content is original writing by Daddy Jim Headquarters based on the One Piece anime series, manga, and official materials. Episode and chapter references are cited where applicable.
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