The 621st One Piece episode sees Franky's robot blast Doflamingo's pair with the General Cannon before the lab escapees arrive. As Baby 5 and Buffalo flee with Caesar, Luffy entrusts the chase to Usopp and Nami, who reel the scientist back in.
Buffalo, impressed by the robot's strength, spins Baby 5 on a chain as Sickle Girl and impales General Franky's left arm. Franky credits them for cracking his armor but likens the duo to a mantis facing a battleship, then yanks the chain to throw Buffalo off balance and unloads his strongest attack, the General Cannon. The pair are sent reeling yet refuse to surrender, both vowing to seize Caesar no matter the cost so as not to shame Joker's name. Franky, spotting the fallen scientist on the tanker, confirms that the two are after him.
With the exit in sight, Usopp begs Nami for wind, and the whole cart cheers as it bursts free of the collapsing lab. The boys gawk at the robot while the women look distinctly unimpressed. Realizing the alliance has turned the odds against them, Baby 5 and Buffalo grab Caesar and take to the air. Law moves to stop them, but Luffy waves him off, insisting Usopp has it handled and that the marksman should not be underestimated. Nami adds that a real alliance demands trust, and that she wants a turn after only running.
Usopp grows his Kuro Kabuto from Bakun Grass, which devours nearby scrap. Nami launches a giant weather egg that swells into a storm cloud and strikes the fleeing pair with Thunder Breed Tempo, knocking Baby 5 unconscious. Usopp follows with a barrage of stone shot, and as Caesar slips free to flee alone, a final Seastone-cuff round clamps around his neck. Everyone celebrates Usopp's boast that he will fight any enemy with their back turned. Far off, Doflamingo keeps flying toward the island, while a drowsy shadow atop a giant penguin wonders how to reach Punk Hazard.

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Based on Chapter 695, the installment introduces Camel and a string of new techniques. Baby 5 uses Flying Disc Girl and Fire Girl, moves absent from the manga, and Nami generates her wind with Gust Sword. Added footage shows G-5 Marines nearly tumbling from the rail car. This also marks the first on-screen appearance of Doflamingo's Ito Ito no Mi strings, glimpsed briefly as they cut through a flock of gulls.
In One Piece Episode 621, General Franky blasts Baby 5 and Buffalo with his General Cannon, and after the lab escapees flee with Caesar Clown in tow, Usopp and Nami team up to recapture the scientist as he tries to slip away.
Yes, after Baby 5 and Buffalo try to fly off with Caesar Clown, Nami's storm attack knocks out Baby 5 and Usopp's stone shot and Seastone cuff bring Caesar back into custody.
After tanking Baby 5's chained Sickle Girl strike, General Franky yanks Buffalo off balance and unleashes his strongest attack, the General Cannon.
Nami summons a storm cloud and strikes Baby 5 with Thunder Breed Tempo, then Usopp follows with a barrage of stone shot and clamps a Seastone cuff around Caesar Clown's neck as he tries to flee alone.
Episode 621 introduces the character Camel along with Baby 5's Flying Disc Girl and Fire Girl techniques, Nami's Gust Sword, and the first glimpse of Doflamingo's Ito Ito no Mi strings.
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View on FandomThis content is original writing by Daddy Jim Headquarters based on the One Piece anime series, manga, and official materials. Episode and chapter references are cited where applicable.
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