Super Buu's most horrifying technique. He raises one hand and fires millions of individual ki blasts that seek out and kill every single human being on Earth in seconds. Only those at Kami's Lookout survive.
The Human Extinction Attack is simple in execution and apocalyptic in scale. Super Buu raises his left arm and fires an enormous wave of individual pink energy blasts into the sky. Each blast independently seeks out a living human being on Earth's surface, homing in with perfect accuracy. Millions of tiny beams arc across the sky like deadly fireworks before plummeting down and killing their targets. Within seconds, every human being on the planet is dead, except for those standing on Kami's Lookout, which exists above the range of the attack, and Mr. Satan and the puppy Bee, whom Buu subconsciously spares.
The context makes the technique even more chilling. Super Buu isn't fighting anyone when he uses it. He's just tired of waiting. Goku had promised that a strong fighter would arrive to challenge Buu, buying time for Goten and Trunks to learn the Fusion Dance. When the time runs out and the promised opponent doesn't appear, Buu walks to the edge of the Lookout, looks down at the planet, and mutters "Time to kill..." Then he casually exterminates humanity.
The Z Fighters on the Lookout can only watch in horror as the energy beams rain across the globe. Chi-Chi, Bulma, and the others realize with growing dread that everyone they know down below is being slaughtered. It's one of the darkest moments in the entire franchise, made worse by how effortlessly Buu accomplishes it.
Fused Zamasu uses a conceptually similar technique in Super, raining energy blasts across the landscape as part of his "Zero Mortals Plan." However, Zamasu's version is more indiscriminate and theatrical, while Super Buu's original is terrifyingly precise: one blast per person, no wasted energy.
The technique's Japanese name, Jinrui Zetsumetsu Kogeki, translates literally to "Human Race Annihilation Attack," which is as blunt and horrifying as the technique itself. Video games use various names: Assault Rain in the Xenoverse and Dragon Ball Heroes series, Genocide Blast in some versions, and Energy Shower in others. Regardless of the name, it always functions the same way: a mass-targeted energy barrage that eliminates entire populations.
In the Xenoverse games, it's a learnable Ultimate Skill and comes as the default option for Buu-type characters. Kid Buu also uses the technique, as does Janemba in Xenoverse 2. The attack's terrifying efficiency and homing capability make it one of the most conceptually disturbing abilities in Dragon Ball, even in a franchise full of planet-destroying attacks.

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